Amber Heard made her debut in the 2004 American sports drama film ‘Friday Night Lights’ directed by Peter Berg. The film opened to positive reviews and was a box office success. Following her debut, she went on to star in films like ‘Drop Dead Sexy’ (2005), ‘North Country’ (2005), ‘Alpha Dog’ (2006), ‘All the Boys Love Mandy Lane’ (2006), ‘Spin’ (2007), and ‘Remember the Daze’ (2007). In 2008, she starred as ‘Baja Miller’ in the American martial arts film ‘Never Back Down’ directed by Jeff Wadlow. Even though the film saw negative reviews upon release, it managed to come out as a financial success. That same year, she also appeared in the American stoner comedy film ‘Pineapple Express’ where she played the role of ‘Angie Anderson.’ The film received a positive response from critics and was a major box office success, grossing over $102.4 million on a budget of $26 million. The following year, she joined the cast of the American zombie comedy film ‘Zombieland’ directed by Ruben Fleischer. The film earned praise from critics and did decent business at the box office.
The year 2010 saw the release of the American supernatural psychological horror film ‘The Ward’ directed by John Carpenter. The film received mostly negative reviews from critics. In 2011, she starred as ‘Piper’ in the American action horror film ‘Drive Angry’ directed by Patrick Lussier. The film was a box office disappointment despite opening to mixed reviews. She next appeared in films like ‘The Rum Diary’ (2011), ‘Syrup’ (2013), ‘Paranoia’ (2013), ‘Machete Kills’ (2013), ‘3 Days to Kill’ (2014), ‘The Adderall Diaries’ (2015), ‘One More Time’ (2015), and ‘Magic Mike XXL’ (2015). She portrayed ‘Ulla Paulson’ in the 2015 biographical romantic drama film ‘The Danish Girl’ directed by Tom Hooper. The film received mostly positive reviews and was a major financial success. In 2017, she starred as ‘Mera’ in the American superhero film ‘Justice League’ directed by Zack Snyder. Despite opening to mixed reviews, the film tanked at the box office.
Heard reprised her role as ‘Mera’ in the 2018 American superhero film ‘Aquaman’ directed by James Wan. The film earned praise from critics and was a massive box office success, becoming the fifth-highest-grossing film of 2018. In 2021, she again returned to play ‘Mera’ in the 2021 director's cut of the 2017 American superhero film ‘Justice League.’ Heard is all set to appear in the upcoming American superhero film ‘Aquaman and the Lost Kingdom’ directed by James Wan.