Demi Moore made her screen debut in the 1981 Silvio Narizzano-directed drama film ‘Choices’ where she played the role of ‘Corri.’ In 1982, she joined the cast of the American daytime television soap opera ‘General Hospital’ created by Frank & Doris Hursley. She played the role of ‘Jackie Templeton’ and remained a part of the show until 1984. She next played the role of ‘Nicole "Nikki" Hollis’ in the 1984 American romantic comedy film ‘Blame It on Rio’ directed by Stanley Donen. The film received mostly negative reviews from critics. That same year, she also appeared in the American comedy-drama film ‘No Small Affair’ which received a mixed critical response. Moore continued to star in films like ‘St. Elmo's Fire’ (1985), About Last Night…’ (1986), ‘One Crazy Summer’ (1986), ‘The Seventh Sign’ (1988), ‘We're No Angels’ (1989), ‘Ghost’ (1990), ‘Nothing but Trouble’ (1991), and ‘Mortal Thoughts’ (1991). In 1992, she portrayed ‘LCDR JoAnne Galloway’ in the American legal drama film ‘A Few Good Men’ directed by Rob Reiner. The film received a positive response from critics and was a box office success, grossing over $243.2 million on a $33–40 million budget. The following year, she starred as ‘Diana Murphy’ in the American erotic thriller film ‘Disclosure’ directed by Barry Levinson. Despite opening to a mixed critical reception, the film was a major financial success and grossed over $214 million on a budget of $55 million.
She continued to star in films like ‘Disclosure’ (1994), ‘The Scarlet Letter’ (1995), ‘The Juror’ (1996), ‘The Hunchback of Notre Dame’ (1996), and ‘Striptease’ (1996). In 1997, she played the role of ‘Lieutenant Jordan O'Neil’ in the Ridley Scott-directed American war drama film ‘G.I. Jane.’ The film received a mixed response from critics and ultimately tanked at the box office. She was next seen in films like ‘Passion of Mind’ (2000), ‘The Hunchback of Notre Dame II’ (2002), ‘Charlie's Angels: Full Throttle’ (2003), ‘Half Light’ (2005), ‘Bobby’ (2006), ‘Mr. Brooks’ (2007), ‘Flawless’ (2008), ‘Happy Tears’ (2010), ‘Bunraku’ (2010), ‘Margin Call’ (2011), ‘LOL’ (2012), ‘Very Good Girls’ (2013), ‘Forsaken’ (2015), ‘Wild Oats’ (2016), ‘Rough Night’ (2017), ‘Love Sonia’ (2018), ‘Corporate Animals’ (2019), and ‘Songbird’ (2020). She was last seen in the 2022 American action comedy film ‘The Unbearable Weight of Massive Talent’ directed by Tom Gormican. The film, despite receiving positive reviews from critics, failed to perform at the box office. Moore will be next seen in the upcoming American drama film ‘Please Baby Please.’