Dane DeHaan was first seen in Episode: "Lunacy" of the American crime drama television series ‘Law & Order: Special Victims Unit’ in 2008. He made his big-screen debut in the 2010 American-Philippine drama film ‘Amigo’ directed by John Sayles. The film received a positive response from critics, earning a 60% approval rating on Rotten Tomatoes. In 2012, he starred as ‘Andrew Detmer’ in the American found footage science fiction action film ‘Chronicle’ directed by Josh Trank. The film opened to a positive reception and performed well at the box office, grossing over $126.6 million on a $12 million budget. The same year, he also appeared in the American biographical historical drama film ‘Lincoln’ directed by Steven Spielberg. The film saw critical acclaim upon release and grossed over $275.3 million on a budget of $65 million. The following year, he portrayed ‘Lucien Carr’ in the American biographical drama film ‘Kill Your Darlings’ directed by John Krokidas. The film received mostly positive reviews from critics and scored a 76% approval rating on Rotten Tomatoes. DeHaan also received a ‘Gotham Award’ nomination for his performance in the film. The same year also saw the release of the American thriller concert film ‘Metallica: Through the Never’ where DeHaan played the role of ‘Trip.’ While the film garnered much praise from critics upon release, it failed to perform at the box office.
In 2014, he starred as ‘Harry Osborn / Green Goblin’ in the Marc Webb-directed American superhero film ‘The Amazing Spider-Man 2.’ The film opened to mixed reviews and while it grossed over $709 million on a $200–293 million budget, it was still considered a financial disappointment. DeHaan was next seen in films like ‘Knight of Cups’ (2015), ‘Life’ (2015), ‘Ballerina’ (2016), ‘Two Lovers and a Bear’ (2016), ‘A Cure for Wellness’ (2017), ‘Valerian and the City of a Thousand Planets’ (2017), ‘The Boxcar Children: Surprise Island’ (2018), and ‘The Kid’ (2019). He was last seen playing the role of ‘Clayton Peterson’ in the 2022 American true-crime drama streaming television miniseries ‘The Staircase.’