Natalie Dormer made her debut in the 2005 American romance film ‘Casanova’ directed by Lasse Hallström. The film opened to mixed reviews but tanked at the box office. That same year, she also made her first television appearance in the British comedy-drama show ‘Distant Shores.’ In 2007, she starred as ‘Cassie’ in the British fictional heist crime film ‘Flawless’ directed by Michael Radford. The film received mixed reviews from critics. Around the same time, she joined the cast of the historical fiction television series ‘The Tudors’ where she played the role of ‘Anne Boleyn.’ She bagged 2 ‘Gemini Award’ nominations for her performance and remained a part of the show until 2008. In 2012, she became a part of the American fantasy drama television series ‘Game of Thrones.’ She played the role of ‘Margaery Tyrell’ and remained on the show until 2016.
Dormer portrayed ‘Queen Elizabeth’ in the 2011 British historical romantic drama film W.E. The film was panned by critics and was a commercial failure. That same year, she appeared in the American superhero film ‘Captain America: The First Avenger’ directed by Joe Johnston. The film earned praise from critics and was a financial success. In 2013, she starred as ‘Nurse Gemma’ in the biographical sports film ‘Rush’ directed by Ron Howard. The film was a critical and commercial success. The year 2014 saw the release of the American dystopian science fiction war film ‘The Hunger Games: Mockingjay – Part 1’ where Dormer was seen playing the role of ‘Cressida.’ The film received mostly positive reviews and was a major box office success, grossing over $755.4 million on a budget of $125–140 million. She reprised her role as ‘Cressida’ in ‘The Hunger Games: Mockingjay – Part 2’ which was also a massive financial success.
In 2017, she starred as ‘Sara Price/Jess Price’ in the American supernatural horror film ‘The Forest’ directed by Jason Zada. Despite opening to mostly negative reviews, the film managed to come out as a box office success. The following year, she appeared in the thriller film ‘In Darkness’ directed by Anthony Byrne. The film received mixed reviews from critics. Dormer was also one of the writers of the film. In 2019, she was seen playing the role of ‘Eliza Merrett’ in the biographical drama film ‘The Professor and the Madman’ directed by P. B. Shemran. The film saw negative reviews upon release. In 2020, she joined the cast of the American historical dark fantasy television series ‘Penny Dreadful: City of Angels’ where she played the role of ‘Lewis Michener.’