Polish-American actress Dagmara Domińczyk made her acting debut on stage in 1999. The following year, she made her screen debut with director Edward Norton’s comedy romance drama film ‘Keeping the Faith’. In 2001, she played the role of Tania Asher in the musical comedy drama ‘Rock Star’ and thereafter bagged her breakthrough role in the action-adventure drama film ‘The Count of Monte Cristo’. The Kevin Reynolds directed 2002 movie was an adaptation of Alexandre Dumas’s 1844 novel of the same name and had her playing the role of Mercédès. The movie received positive reviews and was a commercial success too. The same year, she also appeared in the horror mystery thriller ‘They’. She was next seen in the thriller ‘Tough Luck’ (2003), the biographical romance drama ‘Kinsey’ (2004), the romantic comedy drama ‘Trust the Man’ (2005), the drama ‘Mentor’, the biographical crime drama ‘Lonely Hearts’, the comedy drama ‘Running with Scissors’ (all 2006) and the horror thriller ‘Prisoner’ (2007). Meanwhile, she also made her television debut and acted in several series like ‘Third Watch’ (2001, 2 episodes), ‘Law & Order: Special Victims Unit’ (2003, 1 episode), ‘24’ (2005, 2 episodes) and ‘The Bedford Diaries’ (2006). Apart from these, she also appeared in few television films ‘Bad Apple’, ‘The Five People You Meet in Heaven’ (both 2004) and ‘Hitched’ (2005).
After appearing as Eve in the comedy drama film ‘Helena from the Wedding’ in 2010, she bagged another major role of her career, that of Annika in 'Higher Ground'. The 2011 drama film about a woman’s lifelong struggle with her faith had Vera Farmiga in the lead role (also the director of the movie) with Dagmara Domińczyk playing the role of her best friend. The film received generally favourable reviews and has a Rotten Tomato approval score of 82%. Thereafter, she played the roles of Elizabeth McIntyre in Jay Anania's thriller drama 'The Letter' (2012), Sophi Zubov in Todd Robinson's submarine thriller 'Phantom'(2013), Belva in James Gray's romance drama 'The Immigrant' (2013), Sue in Wladyslaw Pasikowski's thriller 'Jack Strong' (2014), Elizabeth Taylor in Adriana Trigiani's comedy romance 'Big Stone Gap' (2014) and Stacy in Scott Foley's crime comedy 'Let's Kill Ward's Wife' (2014). On television, she acted in an episode each of tv series ‘The Good Wife’, ‘Suits’ (both 2011), ‘Person of Interest’ (2012) and ‘Boardwalk Empire’ (2014).
Continuing her work in film, she played the roles of Nadia in Elisabeth Subrin’s directed drama film ‘A Woman, a Part’ (2016), Rebecca in Fernando Grostein Andrade's comedy drama ‘Abe’ (2019) and Ellen in Kitty Green's drama 'The Assistant' (2019). In between, in 2018, she was roped in to play the role of Karolina Novotney, the PR head and a member of legal team of Waystar RoyCo in HBO’s satirical black comedy-drama television series ‘Succession’. In the first season of the series, she had a recurring role; however, for the following two seasons, she was made a part of the main cast. For her work in the series, Dagmara Domińczyk, along with other cast members, received the 2022 ‘Screen Actors Guild Awards’ for Outstanding Performance by an Ensemble in a Drama Series. In 2021, she became a part of Olivia Colman and Dakota Johnson starrer psychological drama film ‘The Lost Daughter’. The film was based on Elena Ferrante's 2006 novel of the same name and earned critical appreciation as well as several awards (and nominations).
In 2022, she lent her voice to the lead character of Zelma, a woman who is torn between conventional views on marriage and her own happiness, in the comedy drama animation movie ‘My Love Affair with Marriage’. The same year Dagmara Domińczyk played the role of FBI agent Erika Jensen in the 6-episode miniseries ‘We Own This City’ which was about the rise and fall of the Baltimore Police Department's Gun Trace Task Force.
Her television credits, during this period, also include working in an episode each of tv series ‘The Deuce’ (2018) and ‘Prodigal Son’ (2020) as well as a couple of episodes of miniseries ‘The Accidental Wolf’ (2020-2022). She will next be seen in a recurring role in the science fiction dramady ‘Hello Tomorrow!’ as well as a drama film ‘Tonight at Noon’ and a comedy film ‘Bottoms’.