After modeling for many famous brands, including Chanel, Victoria's Secret, and Giorgio Armani, Famke Janssen made her film debut in the 1992 crime-drama ‘Fathers & Sons,’ where she played the role of ‘Kyle Christian.’ That same year, she also made her television debut in the science-fiction series ‘Star Trek: The Next Generation.’ She next appeared in the Oley Sassone-directed crime-thriller ‘Relentless IV: Ashes to Ashes’ in 1994.
In 1995, Famke Janssen was seen in the 'Lord of Illusions,' a neo-noir supernatural horror film based on a short film by Clive Barker, who was also the director of the movie. While the film received a mixed reception, it barely managed to gain back its budget. Famke Janssen next appeared in the James Bond film ‘GoldenEye' (1995), where she portrayed the famous character ‘Xenia Onatopp.’ The movie received critical acclaim and became a blockbuster hit.
After the grand success of ‘GoldenEye,’ Janssen appeared in movies like Dead Girl (1996) and ‘City of Industry’ (1997). In 1998, Famke Janssen was seen in ‘Monument Ave’ and ‘The Gingerbread Man.’ Both movies received a positive response from the audience but failed to generate good numbers at the box office. In the same year, appeared in the action-horror film ‘Deep Rising.’ While the movie failed to make much impact upon its release, it has now achieved a cult status.
In the year 2000, Famke Janssen starred in the superhero film ‘X-Men’ directed by Bryan Singer. She played the role of ‘Jean Grey,’ a mutant with the powers of telepathy and telekinesis. Famke earned a ‘Blockbuster Entertainment Award’ nomination for her role in the movie. In 2001, Janssen featured as ‘Agatha "Aggie" Conrad’ in the crime-thriller ‘Don't Say a Word.’ Even though the movie was panned by the critics, it still managed to earn $100 million against a budget of $50 million.
Famke next starred in the Betty Thomas-directed spy-comedy film ‘I Spy’ in 2002. The next year, she reprised her role as ‘Jean Grey’ in ‘X2.’ Famke Janssen was next seen in ‘Eulogy’ (2004) and ‘Hide and Seek’ (2005). The year 2006 saw the release of the third installment of the X-Men series, ‘X-Men: The Last Stand,’ where she continued her role as ‘Jean Grey’ and won a ‘Saturn Award’ for Best Supporting Actress for her role.
In 2007, Famke starred in the drama film ‘Turn the River’ directed by Chris Eigeman. The movie opened to a positive reception and earned Famke two ‘Hamptons International Film Festival’ awards. From here on, Famke Janssen went on to appear in many commercially successful movies like ‘Taken’ (2008), Taken 2 (2012), ‘Hansel & Gretel: Witch Hunters’ (2013), and ‘The Wolverine’ (2013). In 2014, Janssen played a cameo in the ‘X-Men: Days of Future Past.’ She also appeared in ‘Taken 3’ that same year. In 2017, she starred as ‘Katey Ford’ in the action-comedy film ‘Once Upon a Time in Venice.’ The film was both a critical and commercial failure.
In 2021, Famke Janssen appeared in the Jaume Balagueró-directed ‘The Vault,’ which released on Netflix.
On television, Janssen is known for starring in the dramas 'Nip/Tuck' (2004-2010), 'Hemlock Grove' (2013-15), 'How to Get Away with Murder' (2015-19), 'The Blacklist' (2016-18) and 'The Blacklist: Redemption' (2017).
She was also seen in the action thriller film ‘Dangerous,' which release on November 5, 2021. Famke Janssen will also star in the upcoming romance film ‘Redeeming Love.’