Eiza González made her screen debut in the Mexican melodrama telenovela ‘Lola: Once Upon a Time’ in 2007. She played the role of ‘Dolores "Lola" Valente’ and remained a part of the show until it went off-air in 2008. González made her big-screen debut in the 2008 Jimmy Hayward and Steve Martino-directed American computer-animated adventure comedy film ‘Horton Hears a Who!’ where she voiced ‘Jessica Quilligan.’ The film received positive reviews from critics and was a commercial success, grossing over $298.6 million on a budget of $85 million. That same year, she joined the cast of the Mexican telenovela ‘Mañana es para siempre’ as ‘Cecilia Acosta de Elizalde.’ The series aired 160 episodes and went off-air in 2009. She continued to star in television series like ‘Mujeres asesinas’ (2009), ‘Sueña conmigo’ (2010-2011), ‘Amores verdaderos’ (2012-2013), and ‘From Dusk till Dawn: The Series’ (2014-2016). In 2015, she starred as ‘Sheila "Jetta" Burns’ in the American musical drama film ‘Jem and the Holograms’ directed by Jon M. Chu. The film was largely panned by critics and was a commercial failure. She next played the role of ‘Monica "Darling" Castello’ in the 2017 action film ‘Baby Driver’ directed by Edgar Wright. The film garnered praise from critics and grossed over $226.9 million on a $34 million budget.
In 2018, she starred as ‘Caralala’ in the Robert Zemeckis-directed American drama film ‘Welcome to Marwen.’ The film received a mixed response from critics and was a box office bomb. The following year, she played the role of ‘Nyssiana’ in the American cyberpunk action film ‘Alita: Battle Angel’ directed by Robert Rodriguez. The film received mixed to positive reviews from critics and grossed over $405 million at the box office. That same year, she also starred as ‘Magarita / Madame M’ in the American action comedy film ‘Hobbs & Shaw’ directed by David Leitch. The film opened to a mixed reception but was a decent financial success, grossing over $760 million on a budget of $200 million. She continued to star in films such as ‘Bloodshot’ (2020), ‘I Care a Lot’ (2020), ‘Godzilla vs. Kong’ (2021), and ‘Spirit Untamed’ (2021). González was last seen in the 2022 American heist action thriller film ‘Ambulance’ directed by Michael Bay. The film received mixed reviews from critics and underperformed at the box office.